UConn HealthNew England Musculoskeletal Institute

Physician Profile

Photo of Cato T. Laurencin, M.D., Ph.D.Cato T. Laurencin, M.D., Ph.D.

Dr. Laurencin is a designated University Professor at the University of Connecticut. He is the Albert and Wilda Van Dusen Distinguished Endowed Chair Professor of Orthopaedic Surgery in the School of Medicine. In addition, Dr. Laurencin is a tenured member of the faculty in the School of Engineering and is Professor of Chemical and Biomolecular Engineering, Professor of Materials Engineering and Professor of Biomedical Engineering at UConn. Dr. Laurencin serves as Chief Executive Officer of the Connecticut Institute for Clinical and Translational Science, UConn’s cross-university translational science institute. In addition, he is the Founding Director of the Institute for Regenerative Engineering and the Founding Director of the Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences at the UConn Health Center.

Dr. Laurencin is an elected member of the Institute of Medicine of the National Academy of Sciences and an elected member of the National Academy of Engineering.

Dr. Laurencin previously served as the UConn Health Center’s Vice President for Health Affairs and Dean of the UConn School of Medicine. Prior to that Dr. Laurencin was the Lillian T. Pratt Distinguished Professor and Chair of the Department of Orthopaedic Surgery at the University of Virginia, as well as the Orthopaedic Surgeon-in-Chief at the University of Virginia Health System. In addition, he was designated as a University Professor at the University of Virginia by the President and held professorships in biomedical engineering and chemical engineering.

Dr. Laurencin earned his undergraduate degree in chemical engineering from Princeton University and his medical degree, Magna Cum Laude from the Harvard Medical School. During medical school, he also earned his Ph.D. in biochemical engineering/biotechnology from the Massachusetts Institute of Technology.

An expert in shoulder and knee surgery, Dr. Laurencin has been named to America’s Top Doctors, and America’s Top Surgeons. He is a Fellow of the American College of Surgeons, a Fellow of the American Academy of Orthopaedic Surgeons and is one of few orthopaedic surgeons elected to the American Surgical Association. He is the winner of the Nicolas Andry Award from the Association of Bone and Joint Surgeons.

Dr. Laurencin’s research involves tissue engineering, biomaterials science, nanotechnology and stem cell science and a new field he terms, regenerative engineering. He is an International Fellow in Biomaterials Science and Engineering and a Fellow of the American Institute for Medical and Biological Engineering, and a Fellow of the Biomedical Engineering Society. His work was honored by Scientific American Magazine as one of the 50 greatest achievements in science in 2007. Dr. Laurencin was named the 2009 winner of the Pierre Galletti Award, Medical and Institute of Chemical Engineers at its centennial celebration. Dr. Laurencin is active in technology development. In 2012 his work in musculoskeletal tissue regeneration was featured in National Geographic Magazine's “100 Discoveries that Changed Our World” edition. In addition, he received the Technology, Innovation and Development Award from the Society for Biomaterials in 2013 for key scientific and technical innovation and leadership in translational research.

Dr. Laurencin’s work in mentoring students is well known. He received the Presidential Award for Excellence in Science, Mathematics and Engineering Mentoring in ceremonies at the White House in 2010 and the Beckman Award for Mentoring in 2012. Most recently Dr. Laurencin was honored by the American Association for Advancement of Science, receiving the AAAS Mentor Award.

Dr. Laurencin has lectured throughout the world on clinical orthopaedic surgery and musculoskeletal research. He is an elected member of the Third World Academy of Sciences, and an elected member of the African Academy of Sciences.

Dr. Laurencin is active in science and health policy. He has been a member of the National Science Foundation’s Advisory Committee for Engineering (ADCOM), and has served both on the National Science Board of the FDA, and the National Advisory Council for Arthritis, Musculoskeletal and Skin Diseases at the NIH. Dr. Laurencin is currently a member of the National Academies Board of Life Sciences, and the National Academies Division Committee on Engineering and Physical Sciences (DEPSCOM). He currently holds appointments by the Secretary of Health and Human Services to the National Advisory Council for Biomedical Imaging and Bioengineering, and the Advisory Committee to the Director of the National Institutes of Health.


  • University Professor, UConn
  • Endowed Chair Professor, Department of Orthopaedic Surgery, UConn Health Center
  • Tenured Professor, School of Engineering



American Board of Orthopaedic Surgery

B.S.E., Princeton University
Ph.D., Massachusetts Institute of Technology
M.D., Harvard Medical School (Magna Cum Laude)

State Licensure

Harvard Combined Orthopaedic Surgery Program
Chief Resident, Orthopaedic Surgery, Harvard Medical School, Beth Israel Hospital

Cornell University Medical Center/The Hospital for Special Surgery: Shoulder Surgery and Sports Medicine


  • 2013, Technology, Innovation and Development Award from the Society for Biomaterials
  • 2013, American Association for the Advancement of Science Mentoring Award
  • 2012, National Geographic Magazine Selected Laurencin’s Work in Regenerative Medicine Among the “100 Scientific Discoveries that Changed the World”
  • 2012, Elizabeth Hurlock Beckman Award for Inspiring Their Former Students to Make a Significant Contribution to Society
  • 2012, Dr. Martin Luther King, Jr. Leadership Award, Massachusetts Institute of Technology
  • 2011, Elected to the National Academy of Engineering
  • 2011, Elected to the African Academy of Sciences
  • 2011, Biomedical Engineering Society’s (BMES) Diversity Award
  • 2009, Presidential Award of Excellence in Science, Engineering and Math Mentoring (Presented by President Barack Obama, January 2010)
  • 2009, Pierre Galletti Award (Organization’s Highest Award) American Institute for Medical and Biological Engineering
  • 2008, One of the Top 50 Innovators, Scientific American
  • 2007, Who’s Who in Engineering Higher Education, Academic Keys
  • 2007, Robert A. Bland Award, College of Engineering, University of Virginia
  • 2006, Nicolas Andry Award by the American Association of Bone and Joint Surgeons for Significant Achievements in Orthopaedic Surgery
  • 2006, America’s Top Surgeons
  • 2005, 2004, Americas’ Top Doctors
  • 2004, Elected to National Academy of Sciences, Institute of Medicine
  • 2004, Who’s Who in America
  • 2002, William Grimes Award, American Institute of Chemical Engineers
  • 2002, Distinguished Professor Designation Bestowed, Drexel University
  • 1998, Distinguished Alumni Award, Princeton University
  • 1997, Elected Fellow, American Academy of Orthopaedic Surgeons
  • 1992, Who’s Who in Engineering and Science
  • 1987, Robinson Memorial Prize for Surgery
  • 1984-1987, Hugh Hampton Young Memorial Prize, MIT

Selected Publications
Foley P.L., Ulery B.D., Kan H.M., Burks M.V., Cui Z., Wu Q., Nair L.S., Laurencin C.T. A chitosan thermogel for delivery of ropivacaine in regional musculoskeletal anesthesia. Biomaterials. 2013 Mar; 34(10):2539-46.

Laurencin C.T., Khan Y. Regenerative engineering. Sci Transl Med. 2012 Nov 14; 4(160):160ed9.

Jabbarzadeh E., Deng M., Lv Q., Jiang T., Khan Y.M., Nair L.S., Laurencin C.T. VEGF-incorporated biomimetic poly(lactide-co-glycolide) sintered microsphere scaffolds for bone tissue engineering. J Biomed Mater Res B Appl Biomater. 2012 Nov; 100(8):2187-96.

Lo K.W., Ashe K.M., Kan H.M., Laurencin C.T. The role of small molecules in musculoskeletal regeneration. Regen Med. 2012 Jul; 7(4):535-49.

Peach M.S., James R., Toti U.S., Deng M., Morozowich N.L., Allcock H.R., Laurencin C.T., Kumbar S.G. Polyphosphazene functionalized polyester fiber matrices for tendon tissue engineering: in vitro evaluation with human mesenchymal stem cells. Biomed Mater. 2012 Aug; 7(4):045016.

Amini A.R., Adams D.J., Laurencin C.T., Nukavarapu S.P. Optimally porous and biomechanically compatible scaffolds for large-area bone regeneration. Tissue Eng Part A. 2012 Jul; 18(13-14):1376-88.

Lo K.W., Ulery B.D., Ashe K.M., Laurencin C.T. Studies of bone morphogenetic protein-based surgical repair. Adv Drug Deliv Rev. 2012 Sep; 64(12):1277-91.

Amini A.R., Laurencin C.T., Nukavarapu S.P. Differential analysis of peripheral blood- and bone marrow-derived endothelial progenitor cells for enhanced vascularization in bone tissue engineering. J Orthop Res. 2012 Sep; 30(9):1507-15.

Peach M.S., Kumbar S.G., James R., Toti U.S., Balasubramaniam D., Deng M., Ulery B., Mazzocca A.D., McCarthy M.B., Morozowich N.L., Allcock H.R., Laurencin C.T. Design and optimization of polyphosphazene functionalized fiber matrices for soft tissue regeneration. J Biomed Nanotechnol. 2012 Feb; 8(1):107-24.

Deng M., James R., Laurencin C.T., Kumbar S.G. Nanostructured polymeric scaffolds for orthopaedic regenerative engineering. IEEE Trans Nanobioscience. 2012 Mar; 11(1):3-14.

Amini A.R., Laurencin C.T., Nukavarapu S.P. Bone tissue engineering: recent advances and challenges. Crit Rev Biomed Eng. 2012; 40(5):363-408.

Kumbar SG, Toti US, Deng M, James R, Laurencin CT, Aravamudhan A, Harmon M, Ramos DM. Novel mechanically competent polysaccharide scaffolds for bone tissue engineering. Biomed Mater. 2011 Dec; 6(6):065005.

Ulery B.D., Nair L.S., Laurencin C.T. Biomedical Applications of Biodegradable Polymers. J Polym Sci B Polym Phys. 2011 Jun 15; 49(12):832-864.

James R., Kumbar S.G., Laurencin C.T., Balian G., Chhabra A.B. Tendon tissue engineering: adipose-derived stem cell and GDF-5 mediated regeneration using electrospun matrix systems. Biomed Mater. 2011 Apr; 6(2):025011.

Bush J.R., Nayak B.K., Nair L.S., Gupta M.C., Laurencin C.T. Improved bio-implant using ultrafast laser induced self-assembled nanotexture in titanium. J Biomed Mater Res B Appl Biomater. 2011 May; 97(2):299-305.

Lo K.W., Kan H.M., Ashe K.M., Laurencin C.T. The small molecule PKA-specific cyclic AMP analogue as an inducer of osteoblast-like cells differentiation and mineralization. J Tissue Eng Regen Med. 2012 Jan; 6(1):40-8.

Paper icon View more publications, see Pubmed listing.

Research Interests

Clinical Research

  • Repair and regeneration of shoulder and knee tissue musculoskeletal regeneration.

Basic Science Research

  • Biomaterials, tissue engineering, nanotechnology, and stem cell technology.

Office Locations

New England Musculoskeletal Institute
UConn Health Center
263 Farmington Avenue
Farmington, CT 06030


Make an Appointment >

A-Z INDEX        UCONN HEALTH        TEXT-ONLY University of Connecticut Health Center
Disclaimer   Privacy Notice
Maps & Directions